Question:
What is the difference between a nucleoside and a nucleotide?
Answer:
The major difference between nucleotide and nucleoside is as follows -
Nucleotide is sugar + base + phosphate. A nucleotide consists of a nitrogenous base, a sugar (ribose or deoxyribose) and one to three phosphate groups.
Nucleoside is sugar + base. A nucleoside consists of a nitrogenous base covalently attached to a sugar (ribose or deoxyribose) but without the phosphate group. When phosphate group of nucleotide is removed by hydrolysis, the structure remaining is nucleoside.
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