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Question:
is physical disability a problem in their gene ? if so how does it happen ?
Answer:

Any physical disability is certainly not a genetic problem. However, some physical disabilities may be due to genetic disorders as well. A common example of this is Muscular dystrophy is a genetic condition where the bodys muscle fibres gradually weaken over time. Children can have different kinds of muscular dystrophy most commonly the Duchenne Muscular Dystrophy.

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